ioDisease Model Cells
ioMicroglia TREM2 R47H/WT
cat no | io1038
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ioDisease Model Cells
ioMicroglia TREM2 R47H/R47H
cat no | io1035 | io1036
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ioDisease Model Cells
ioMicroglia APOE 4/3 C112R/WT
cat no | io1033 | io1034
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ioDisease Model Cells
ioMicroglia APOE 4/4 C112R/C112R
cat no | io1031 | io1032
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ioDisease Model Cells
ioGlutamatergic Neurons APP KM670/671NL / KM670/671NL
cat no | io1059
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ioDisease Model Cells
ioGlutamatergic Neurons APP KM670/671NL/WT
cat no | io1061
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ioDisease Model Cells
ioGABAergic Neurons APP V717I/WT
cat no | io1084 | io1085
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ioDisease Model Cells
ioGABAergic Neurons APP V717I/V717I
cat no | io1081 | io1082
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ioDisease Model Cells
ioGlutamatergic Neurons PSEN1 M146L/WT
cat no | io1072
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ioDisease Model Cells
ioGlutamatergic Neurons PSEN1 M146L/M146L
cat no | io1069
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ioDisease Model Cells
ioGlutamatergic Neurons APP V717I/WT
cat no | io1067
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ioDisease Model Cells
ioGlutamatergic Neurons APP V717I/V717I
cat no | io1063
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ioDisease Model Cells
ioGlutamatergic Neurons PRKN R275W/WT
cat no | io1013
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ioDisease Model Cells
ioGlutamatergic Neurons PRKN R275W/R275W
cat no | io1020
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ioDisease Model Cells
ioGlutamatergic Neurons PINK1 Q456X/WT
cat no | io1079
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ioDisease Model Cells
ioGlutamatergic Neurons PINK1 Q456X/Q456X
cat no | io1076
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ioDisease Model Cells
ioGlutamatergic Neurons SNCA A53T/A53T
cat no | io1088
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ioDisease Model Cells
ioGlutamatergic Neurons GBA null/R159W
cat no | io1007
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ioDisease Model Cells
ioMotor Neurons SOD-1 G93A/WT
cat no | io1042
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ioDisease Model Cells
ioMotor Neurons SOD-1 G93A/G93A
cat no | io1041
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ioDisease Model Cells
ioMotor Neurons FUS P525L/WT
cat no | io1055
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ioDisease Model Cells
ioMotor Neurons FUS P525L/P525L
cat no | io1052
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ioDisease Model Cells
ioMotor Neurons TDP-43 M337V/WT
cat no | io1050
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ioDisease Model Cells
ioMotor Neurons TDP-43 M337V/M337V
cat no | io1046
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ioDisease Model Cells
ioGlutamatergic Neurons TDP-43 M337V/WT
cat no | ioEA1006
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ioDisease Model Cells
ioGlutamatergic Neurons TDP-43 M337V/M337V
cat no | ioEA1005
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ioDisease Model Cells
ioGlutamatergic Neurons MAPT P301S/WT
cat no | io1015
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ioDisease Model Cells
ioGlutamatergic Neurons MAPT P301S/P301S
cat no | io1008
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ioDisease Model Cells
ioGlutamatergic Neurons MAPT N279K/WT
cat no | io1009
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ioDisease Model Cells
ioGlutamatergic Neurons MAPT N279K/N279K
cat no | io1014
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ioDisease Model Cells
ioGlutamatergic Neurons HTT 50CAG/WT
cat no | ioEA1004
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What Scientists Say About ioDisease Models
Dr Mariangela Iovino
Senior Group Leader | Biology Discovery | Charles River
"Data from assays routinely used at Charles River show that 无忧短视频 disease models have disease-relevant phenotypes, suggesting that the cells can be easily applied to drug discovery programs鈥�
Emma Jones, PhD
Senior Scientist | Neurobiology Medicines Discovery Catapult
"More physiologically relevant disease models will permit better and more predictable drug discovery, and will therefore improve the translation of medicines to the clinic"
Wild type and isogenic disease model cells: A true comparison
Be confident in your data by pairing ioDisease Model Cells with the genetically matched ioWild Type control.
The right human model
Are you seeking to solve the paucity of successful treatments for neurodegenerative disease? Learn how ioDisease Model Cells are being used as a physiologically-relevant CNS model for drug discovery that will reproducibly scale to high-throughput screens.
鈥淯ltimately, we hope our ioDisease Model Cells will help provide more effective therapies for neurodegenerative diseases such as Huntington鈥檚 disease. I believe that it is crucial to use the right human model to successfully translate research into the clinic and help patients鈥�
Tony Oosterveen PhD
无忧短视频
A next-generation approach to study Huntington鈥檚 disease
Learn about the benchtop benefits and applications of our latest disease model for Huntington鈥檚 disease, ioGlutamatergic Neurons HTT 50CAG/WT.
Addressing current challenges of in vitro cell models
Discover how experts from across academia and industry are approaching the challenges of accuracy and reproducibility of in vitro cell models as well as potential solutions.
鈥淔or translational applications, it鈥檚 important to identify a model that is relevant, which is mirroring the human disease鈥�
Davide Danovi PhD
King鈥檚 College London
Don鈥檛 see what you鈥檙e looking for?
Partner with us to generate custom ioDisease Model Cells. Access our platform to generate custom disease model cells to answer your drug discovery and disease research questions.
